The Relationship between Clinical Feature, Complex Immunophenotype, Chromosome Karyotype, and Outcome of Patients with Acute Myeloid Leukemia in China

Table 4

Univariate Cox model for OS and RFS risk factors of MPAL, Ly⁺AML, and Ly⁻AML patients.

Risk factors	OS			RFS
	HR	95% CI	value	HR	95% CI	value
Age	1.014	1.001–1.027	0.031	1.013	1.000–1.026	0.055
Gender	1.023	0.68–1.540	0.912	1.150	0.761–1.737	0.507
WBC	1.003	1.001–1.006	0.012	1.002	1.000–1.004	0.102
BM blast	0.996	0.986–1.006	0.429	0.996	0.986–1.006	0.452
Chromosome karyotype
Normal	1.000	—	—	1.000	—	—
Complex	2.409	1.429–4.060	0.001	2.691	1.591–4.553	0.000
Abnormal	1.808	1.018–3.211	0.043	1.718	0.973–3.031	0.062
Immunophenotype
Ly^−AML	1.000	—	—	1.000	—	—
Ly^+AML	1.404	0.768–2.565	0.270	0.808	0.444–1.472	0.486
MPAL	1.446	0.905–2.312	0.023	1.063	0.600–1.545	0.046

HR: hazard ratio; CI: confidence interval; WBC: white blood cell; OS: overall survival; RFS: relapse-free survival.