Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation
Overexpression of Hiwi promotes the growth of HT-29 or Caco-2 cells. (a) and (b): significantly promoted growth of Caco-2 cells (a) or HT-29 cells (b), which were infected with 1 MOI Ad-Hiwi, with 1 MOI Ad-RFP infection as control. The growth of Caco-2 or HT-29 cells which were infected with Ad-Hiwi or with Ad-RFP was evaluated by CCK-8 assay. (c) and (d): difference in cell growth by colony formation assay between the Ad-Hiwi- and Ad-RFP-infected Caco-2 cells at 1 or 10 MOI. Statistical significance was shown as , , and .
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