Clinical Implications and Prognostic Values of Prostate Cancer Susceptibility Candidate Methylation in Primary Nonmuscle Invasive Bladder Cancer

Table 3

Association between PRAC methylation and clinicopathological characteristics.

Variables	Methylation level (%)	value
Normal versus cancer
Normal	17.3 ± 4.0	<0.001^1
Cancer	48.3 ± 24.3
Number of tumors
Single	45.6 ± 24.5	0.117^1
Multiple	52.4 ± 23.7
Tumor size
<3 cm	45.4 ± 25.7	0.095^1
≥3 cm	52.7 ± 21.7
Grade
G1	33.7 ± 19.4	<0.001^2
G2	50.5 ± 23.3
G3	70.8 ± 17.2
T stage
Ta	38.6 ± 24.6	<0.001^1
T1	54.0 ± 22.4
Recurrence
No	43.6 ± 24.3	0.001^1
Yes	59.6 ± 20.5
Progression
No	45.6 ± 23.9	<0.001^1
Yes	69.2 ± 16.4

value calculated using Student’s -test.
value calculated using ANOVA trend analyses test.
PRAC: prostate cancer susceptibility candidate.