Macrophage Migration Inhibitory Factor Promoter Polymorphisms (−794 CATT_5–8 and −173 G>C): Relationship with mRNA Expression and Soluble MIF Levels in Young Obese Subjects

Figure 4

Relative MIF mRNA expression by −794 (rs5844572) and −173 G>C MIF (rs755622) haplotype in normal-weight and obese subjects. (a) The slightly higher MIF mRNA expression was observed in the 6G carriers, while the 5G carriers had a low expression in the total population. (b) The modest increase in MIF mRNA expression was observed in the 6G carriers in both groups. Relative expression analysis was performed using the method, using GAPDH as the reference gene. Comparison among groups was performed using Mann-Whitney -test; .

(a)

(b)