Site-Specific Secretome Map Evidences VSMC-Related Markers of Coronary Atherosclerosis Grade and Extent in the Hypercholesterolemic Swine

Figure 3

IPA of a subset of 31 proteins identified in the secretome of RCA specimens. Pathways were generated based on the information stored in IPA Knowledge base. Nodes correspond to the 31 proteins and are reported with their Gene Codes. Extracellular space, cytoplasm, and plasma membrane proteins are shown based on IPA classification. Relationships with disease and cellular functions are evidenced. The relationships that are predicted to lead to activation and to inhibition and those not predicted are reported in orange, blue, and grey, respectively.