Research Article

NT-proBNP as Early Marker of Subclinical Late Cardiotoxicity after Doxorubicin Therapy and Mediastinal Irradiation in Childhood Cancer Survivors

Table 2

Right and left ventricular TDI parameters in groups with normal and abnormal NT-proBNP.

Systole () Diastole ()Diastole ()
Abnormal
Normal
Abnormal
Normal
Abnormal
Normal

RVFW a3.99 ± 0.815.03 ± 0.19<0.0015.35 ± 1.527 ± 0.68<0.0012.31 ± 0.73.22 ± 0.47<0.001
RVFW m6.03 ± 1.77.2 ± 0.47<0.0018.64 ± 1.8810.4 ± 0.63<0.0014.35 ± 1.416.67 ± 0.52<0.001
RVFW b7.37 ± 1.628.75 ± 0.4<0.00110.79 ± 2.212.1 ± 0,86<0.055.48 ± 1.17.14 ± 0.45<0.001
LVFW a3.28 ± 0.53.89 ± 0.27<0.0015.5 ± 0.955.7 ± 0.47NS2.31 ± 0.723.3 ± 0.32<0.001
LVFW m4.27 ± 0.75<0.0017.6 ± 1.989.7 ± 0.58<0.0013.18 ± 0.554.2 ± 0.56<0.001
LVFW b5.6 ± 1.16.5 ± 1.03<0.0510.48 ± 210.42 ± 0.8NS4.72 ± 0.755.31 ± 0.79<0.05

RVFW a, m, b: right ventricular free wall at the apical, middle, and basal parts, respectively.
LVFW a, m, b: left ventricular free wall at the apical, middle, and basal parts, respectively.
TDI: tissue Doppler imaging.