Predictive Performance of a Seven-Plex Antibody Array in Prenatal Screening for Down Syndrome

Table 2

Ratio of MoM-adjusted serum concentrations per analyte for DS compared to controls. Significance is indicated as ; ; .

	Total cohort (nDS = 170)	Week 10 (nDS = 43)	Week 11 (nDS = 25)	Week 12 (nDS = 77)
PAPP-A (4PL)
PAPP-A (scaled)
PAPP-A (AutoDELFIA)
fβ-hCG (4PL)
fβ-hCG (scaled)
fβ-hCG (autoDELFIA)		1.25
AFP	0.90	1.01	0.85
ANGPTL3	0.98	1.07	0.96	0.92
EGF	1.12	1.17	1.39	0.93
IGFII		1.40	1.47	1.17
SOD1	1.04	1.11	1.14	0.93
IgG	1.13	1.32	1.04	1.04