Research Article

Association of Angiotensin Converting Enzyme Insertion-Deletion Polymorphism with Hypertension in Emiratis with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status

Table 3

Allele and genotype frequency distribution of ACE I/D polymorphisms in T2DM and hypertension cases and controls regardless of obesity status.

Frequency distribution
T2DM Hypertension
Cases ()Controls ()Cases ()Controls ()

Genotypes
 DD124 (44.8%) 112 (37.7%)0.09
<0.0001
98 (41.7%)136 (40.8%)0.86
<0.0001
 ID149 (53.8%)153 (51.5%)135 (57.4%)163 (48.9%)
 II4 (1.4%)32 (10.8)2 (0.9%)34 (10.3%)
Allele frequencies
 D0.720.630.00370.700.650.07
 I0.280.370.300.35

Data shown are numbers and percentages in parentheses unless specified otherwise, Fisher exact test. II versus ID + DD, DD versus ID + II.