Association of Angiotensin Converting Enzyme Insertion-Deletion Polymorphism with Hypertension in Emiratis with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status

Table 4

Evaluation of T2DM and hypertension risk association with ACE DD genotype by obesity status in case-control study.

Association based on obesity status
	Obesity status	ACE genotype	Groups			Logistic regression
			Cases	Control		OR (95% CI)
T2DM	All together	DD	124	112	0.09	1.34 (0.96–1.87)	0.086
		ID + II	153	185
	Obese (BMI > 30)	DD	66	38	0.30	1.34 (0.81–2.23)	0.26
		ID + II	88	68
	Nonobese (BMI < 30)	DD	53	68	0.18	1.41 (0.88–2.28)	0.15
		ID + II	59	107
Hypertension	All together	DD	98	136	0.86	1.02 (0.72–1.42)	0.93
		ID + II	137	197
	Obese (BMI > 30)	DD	50	53	0.02	0.54 (0.33–0.89)	0.01
		ID + II	116	67
	Nonobese (BMI < 30)	DD	46	75	0.03	1.80 (1.08–2.99)	0.02
		ID + II	41	120

Data shown are numbers unless specified otherwise, Fisher exact test.
All together means obese + nonobese and others about whom information on obesity status was not available.