Serum Enzyme Profiles Differentiate Five Types of Muscular Dystrophy

Table 2

Serum enzymes levels among five types of MD.

Category	ALTn ()	ASTn ()	ALPn ()	LDHn ()	CKn ()
DMD	6.55 (4.85–8.18)^b,c,d,e	5.32 (3.98–6.68)^b,c,d,e	1.1 (0.94–1.25)^c,d	4.28 (3.23–5.60)^b,c,d,e	44.77 (31.05–56.57)^b,c,d,e
BMD	2.91 (1.96–4.61)^a,c,d,e	2.85 (1.76–4.5)^a,c,d,e	1.06 ± 0.48	2.02 (1.49–3.48)^a,c,d,e	27.59 (16.64–41.22)^a,c,d,e
FSHD	1.04 ± 0.48^a,b	1.00 (0.87–1.44)^a,b,d	0.60 (0.42–0.92)^a	1.02 (0.93–1.44)^a,b	3.05 (1.64–3.91)^a,b,d
LGMD	1.65 (0.74–3.39)^a,b,e	1.68 (1.01–2.86)^a,b,c,e	0.55 (0.45–1.17)^a	1.49 (1.00–2.37)^a,b	9.08 (4.50–21.87)^a,b,c,e
EDMD	0.50 (0.36–0.83)^a,b,d	0.73 (0.69–1.04)^a,b,d	1.15 ± 0.54	1.09 ± 0.17^a,b	1.64 (0.66–3.51)^a,b,d
H	92.45	111.09	22.83	112.19	114.01
value	<0.001	<0.001	<0.001	<0.001	<0.001

MD, muscular dystrophy; DMD, Duchenne muscular dystrophy; BMD, Becker’s muscular dystrophy; FSHD, facioscapulohumeral dystrophy; LGMD, limb girdle muscular dystrophy; EDMD, Emery-Dreifuss muscular dystrophy; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; LDH, lactic dehydrogenase; CK, creatine kinase.
^aComparing with DMD, .
^bComparing with BMD, .
^cComparing with FSHD, .
^dComparing with LGMD, .
^eComparing with EDMD, .