Serum Enzyme Profiles Differentiate Five Types of Muscular Dystrophy

Table 3

The serum enzymes profile in five types of MD.

Category	ALTn ()	ASTn ()	ALPn ()	LDHn ()
BMD	2.91 (1.96–4.61) (↑)	2.85 (1.76–4.5) (↑)	1.06 ± 0.46 (→)	2.02 (1.49–3.48) (↑)
DMD	6.55 (4.85–8.18) (↑)	5.32 (3.98–6.68) (↑)	1.1 (0.94–1.25) (↑)	4.28 (3.23–5.60) (↑)
EDMD	0.50 (0.36–0.83) (→)	0.73 (0.69–1.04) (→)	1.15 ± 0.54 (→)	1.06 ± 0.19 (→)
FSHD	1.04 ± 0.48 (→)	1.00 (0.87–1.44) (→)	0.60 (0.42–0.92) (→)	1.02 (0.93–1.44) (→)
LGMD	1.65 (0.74–3.39) (↑)	1.68 (1.01–2.86) (↑)	0.55 (0.45–1.17) (→)	1.49 (1.00–2.37) (↑)

MD, muscular dystrophy; DMD, Duchenne muscular dystrophy; BMD, Becker’s muscular dystrophy; FSHD, facioscapulohumeral dystrophy; LGMD, limb girdle muscular dystrophy; EDMD, Emery-Dreifuss muscular dystrophy; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; LDH, lactic dehydrogenase.
“→” represents that patients had similar levels of enzymes comparing with normal people (). “↑” represents that patients had significantly higher levels of enzymes comparing with normal people ().