Research Article

Serum Enzyme Profiles Differentiate Five Types of Muscular Dystrophy

Table 4

The enzymes profile between patients with BMD and LGMD.

CategoryALTn ()ASTn ()ALPn ()LDHn ()

BMD2.91 (1.96–4.61) (↑)2.85 (1.76–4.5) (↑)1.06 ± 0.462.02 (1.49–3.48) (→)
LGMD1.65 (0.74–3.39) (→)1.68 (1.01–2.86) (→)0.55 (0.45–1.17)1.49 (1.00–2.37) (→)

BMD, Becker’s muscular dystrophy; LGMD, limb girdle muscular dystrophy; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; LDH, lactic dehydrogenase.
“→” represents that patients had 2-fold ULN of enzymes levels (compared with “2,” ). “↑” represents that patients had exceeded 2-fold ULN of enzymes levels (compared with “2,” ). As demonstrated in Table 2, there was no significant difference of ALP serum levels in patients with BMD and LGMD, so we did not perform further analysis on magnitude of change in ALP serum levels.