Chaperonin-Containing t-Complex Protein-1 Subunit β as a Possible Biomarker for the Phase of Glomerular Hyperfiltration of Diabetic Nephropathy

Table 1

The general characteristics of subjects with healthy, type 2 diabetes mellitus (DM) with hyperfiltration and nonhyperfiltration groups.

	Healthy	DM with nonhyperfiltration	DM with hyperfiltration
	17	98	49
Sex (male/female)	8/9	55/43	16/33
Age (year)	67.7 ± 12.8^2,3	60.1 ± 12.0^1,3	52.4 ± 9.3^1,2
eGFR	89.3 ± 20.7^3	91.3 ± 14.5^3	138.7 ± 12.4^1,2
FPG (mmo/L)	5.08 ± 0.65^2,3	7.82 ± 2.36^1,3	8.66 ± 2.64^1,2
HgbA1c (%)	—	7.65 ± 1.63	8.23 ± 2.02
Creatinine (umol/L)	72.28 ± 13.71^3	73.348 ± 14.36^3	48.66 ± 8.01^1,2
CHO (mmol/L)	5.26 ± 0.71^2	4.51 ± 0.93^1,3	4.84 ± 0.97^2
TG (mmol/L)	1.12 ± 0.84^3	1.49 ± 0.90	1.85 ± 1.34^1
ACR (μg/mg)	8.05 ± 5.50	11.14 ± 7.14	11.15 ± 5.71

eGFR: estimated glomerular filtrating rate; FPG: fasting plasma glucose; HgbA1c: glycated hemoglobin; CHO: total cholesterol; TG: triglyceride; ACR: ratio of urine microalbumin to creatinine; against health, against DM with nonhyperfiltration, and against hyperfiltration.