Research Article
Influence of GSTM1, GSTT1, and GSTP1 Polymorphisms on Type 2 Diabetes Mellitus and Diabetic Sensorimotor Peripheral Neuropathy Risk
Table 2
Genetic characteristics of studied patients with T2DM and controls.
| | Variable |
T2DM-84, No. (%) |
Controls-98, No. (%) | p value |
| | GSTM1/GSTT1 | 36 (42.8) | 35 (35.7) | Reference | | GSTM1 null/GSTT1 null | 11 (13.1) | 13 (13.3) | 0.67, OR: 1.82
95% CI: (0.32–2.08) | | GSTM1 present/GSTT1 null | 4 (4.7) | 12 (12.2) | 0.09, OR: 0.32
95% CI: (0.09–1.10) | | GSTM1 null/GSTT1 present | 33 (39.3) | 38 (38.7) | 0.61, OR: 0.84
95% CI: (0.43–1.63) | | GSTP1/GSTT1/GSTM1 | | | | | Ile/Ile/present/present | 21 (25.0) | 24 (24.5) | Reference | | Ile/Ile/null/null | 6 (7.1) | 12 (12.2) | 0.40, OR: 0.57
95% CI: (0.18–1.79) | | Ile/Ile/null/present | 3 (3.6) | 8 (8.2) | 0.31, OR: 0.42
95% CI: (0.10–1.82) | | Ile/Ile/present/null | 19 (22.6) | 28 (28.6) | 0.54, OR: 0.77
95% CI: (0.34–1.77) | | Ile/Val/null/null | 3 (3.6) | 1 (1.02) | 0.34, OR: 3.43
95% CI: (0.33–35.5) | | Ile/Val/null/present | 0 (0.0) | 3 (3.06) | — | | Ile/Val/present/null | 10 (11.9) | 7 (7.14) | 0.57, OR: 1.63
95% CI: (0.52–5.05) | | Ile/Val/present/present | 11 (13.1) | 10 (10.2) | 0.79, OR: 1.25
95% CI: (0.44–3.55) | | Val/Val/null/null | 2 (2.4) | 0 (0.0) | — | | Val/Val/null/present | 1 (1.2) | 1 (1.02) | — | | Val/Val/present/null | 4 (4.8) | 3 (3.06) | 0.69, OR: 1.52
95% CI: (0.30–7.6) | | Val/Val/present/present | 4 (4.8) | 1 (1.02) | 0.34, OR: 4.57
95% CI: (0.47–44.2) |
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OR: odd ratio, CI: confidence interval, and No.: number.
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