Research Article

Elevated ZNF703 Protein Expression Is an Independent Unfavorable Prognostic Factor for Survival of the Patients with Head and Neck Squamous Cell Carcinoma

Table 3

Multivariate analysis of different parameters in 210 patients with HNSCC by Cox proportional hazard mode.

Variables OS
RR95% CI

Male0.9550.466–1.9550.899
Complications0.5830.358–0.9510.031
Tobacco consumption0.7550.421–1.3520.344
Alcohol consumption0.5740.358–0.9220.022
Poor differentiation1.2450.798–1.9420.334
ZNF703 high expression1.6351.073–2.4930.022
Stage III/IV2.6611.689–4.1900.000

Variables DFS
RR95% CI

Poor differentiation1.1290.761–1.6740.546
Without neck dissection1.4470.974–2.1490.068
Without adjuvantradiotherapy1.6561.077–2.5460.021
ZNF703 high expression1.4190.999–2.0160.050
Stage III/IV1.7821.205–2.6340.004
Larynx cancer0.5430.351–0.8420.006

RR = relative risk; CI = confidence interval.