Research Article

High Thyroglobulin Antibody Levels Increase the Risk of Differentiated Thyroid Carcinoma

Table 1

Clinical characteristics of the final study cohort.

DTCBenign value

Number ()2371,401
Gender (, %)0.209
Male ()44 (18.6)311 (22.2)
Female ( = 1,283)193 (81.4)1,090 (77.8)
Mean age (yr)43.4 ± 12.948.4 ± 11.1<0.001
Median TSH (mIU/L)1.53 (0.88–2.42)1.05 (0.64–1.78)<0.001
Mean nodule size (cm)2.7 ± 1.93.3 ± 1.6<0.001
Nodule type (, %)<0.001
Solitary ()80 (33.8)241 (17.2)
Multiple ( = 1,317)157 (66.2)1,160 (82.8)
TgAb ≥ 40 IU/mL ()56 (23.6)177 (12.6)<0.001
TPOAb ≥ 50 IU/mL ()30 (12.7)106 (7.6)0.009

TSH levels are presented as median (25th–75th empirical percentiles).
DTC: differentiated thyroid cancer.