Upregulated Expression of SOX4 Is Associated with Tumor Growth and Metastasis in Nasopharyngeal Carcinoma

Figure 1

The expression of SOX4 in NPC. (a) Western blot was performed to detect the expression of SOX4 in 3 NPC tissues and 3 inflammatory nasopharyngeal tissues. (T) Nasopharyngeal squamous cell carcinoma tissues. (N) Inflammatory nasopharyngeal epithelium tissues. β-actin was used as a control. (b) The bar demonstrated the ratio of SOX4 protein expression to β-actin by densitometry. (c) Negative staining of SOX4 in the control inflammatory nasopharyngeal epithelial tissues (×200). (d) High expressions of SOX4 were observed in NPC tissues (×200). (e) High expressions of Ki67 were observed in NPC tissues (×200). (f) Western blot analysis of SOX4 expression in CNE2 and NP69. (g) qRT-PCR was used to detect the relative expression of SOX4 in two cell lines. The data shown were representative of at least three independent experiments. .

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