Upregulated Expression of SOX4 Is Associated with Tumor Growth and Metastasis in Nasopharyngeal Carcinoma

Figure 4

Interference of SOX4 expression suppressed the proliferation of CNE2 cells. (a) CNE2 cells were transiently transfected with siRNA targeting SOX4 (si-1, si-2, si-4, and si-4) or a scrambled sequence (control siRNA). A representative western blot image showed the expression of SOX4. (b) CCK8 assay was used to determine cell viability of CNE2 cells treated with SOX4-siRNA or control siRNA for the indicated time. The data were means ± SEM (). (c) Flow cytometric analysis was used to evaluate cell cycle distribution of CNE2 after being transfected with SOX4-siRNA or control siRNA for 48 h.

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