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Disease Markers
Volume 2015, Article ID 727401, 10 pages
Review Article

Electrocardiographic Predictors of Cardiovascular Mortality

1Department of Functional Sciences, Victor Babes University of Medicine and Pharmacy, 300173 Timisoara, Romania
21st Department of Internal Medicine, Victor Babes University of Medicine and Pharmacy, 300173 Timisoara, Romania

Received 11 January 2015; Revised 20 June 2015; Accepted 2 July 2015

Academic Editor: Donald H. Chace

Copyright © 2015 Ioana Mozos and Alexandru Caraba. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cardiovascular diseases are the main causes of mortality. Sudden cardiac death may also appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The electrocardiogram is used in clinical practice and clinical trials, as a valid, reliable, accessible, inexpensive method. The aim of the present paper was to review electrocardiographic (ECG) signs associated with cardiovascular mortality and the mechanisms underlying those associations, providing a brief description of the main studies in this area, and consider their implication for clinical practice in the general population and athletes. The main ECG parameters associated with cardiovascular mortality in the present paper are the P wave (duration, interatrial block, and deep terminal negativity of the P wave in V1), prolonged QT and Tpeak-Tend intervals, QRS duration and fragmentation, bundle branch block, ST segment depression and elevation, T waves (inverted, T wave axes), spatial angles between QRS and T vectors, premature ventricular contractions, and ECG hypertrophy criteria.