Association between BMP4 rs17563 Polymorphism and NSCL/P Risk: A Meta-Analysis

Table 2

Summary ORs and 95% CI of BMP4 rs17563 T>C polymorphism and NSCL/P risk.

	^*	C vs. T					TC vs. TT					CC vs. TT					TC + CC vs. TT					CC vs. TT + TC
		OR	95% CI		(%)^a	Bon	OR	95% CI		(%)^a	Bon	OR	95% CI		(%)^a	Bon	OR	95% CI		(%)^a	Bon	OR	95% CI		(%)^a	Bon
Total	6	1.17	0.81–1.68	0.40	87.6	1	0.88	0.56–1.38	0.58	81.7	1	1.51	0.72–3.15	0.27	85.9	1	1.01	0.63–1.63	0.96	85.7	1	1.63	0.91–2.90	0.10	80.3	0.49
Ethnicity
Chinese	4	1.52	1.28–1.82	<0.01	0	<0.01	1.21	0.83–1.76	0.32	49.2	1	2.58	1.74–3.82	<0.01	0	<0.01	1.45	1.14–1.84	<0.01	0	0.02	2.46	1.46–4.14	<0.01	47.0	<0.01
Brazilian	2	0.69	0.50–0.96	0.03	68.5	0.14	0.52	0.40–0.68	<0.01	0	<0.01	0.55	0.24–1.26	0.16	79.3	0.78	0.52	0.35–0.78	<0.01	54.4	<0.01	0.83	0.45–1.54	0.55	70.7	1

Numbers of comparisons.
^aThe variation in OR attributable to heterogeneity.
Bon: value with Bonferroni testing of multiple comparisons.