CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer

Table 4

Regression analysis.

Variable (categorization)	Univariable analysis				Multivariable analysis
	HR	95% CI		value	HR	95% CI		value
Tumor stage (pTa versus pT1)	1.481	0.635	3.454	0.363
Histologic grade (WHO 2004)	2.070	0.894	4.808	0.090
Adjacent carcinoma in situ	1.563	0.363	6.711	0.549
Multifocality	1.401	0.565	3.472	0.467
Growth pattern (papillary versus solid)	7.634	2.717	21.740	<0.001	3.891	1.245	12.195	0.019
CD73	0.228	0.053	0.978	0.047	0.319	0.072	1.408	0.132
Ki-67	3.356	1.429	7.874	0.006	2.222	0.873	5.650	0.094

Staging and grading according to the 2004 WHO classification system.