Ehlers-Danlos Syndrome, Hypermobility Type, Is Linked to Chromosome 8p22-8p21.1 in an Extended Belgian Family

Table 3

Ranking of the candidate genes according to different gene prioritization tools with functionally interesting candidates indicated in bold.

	Endeavour	Suspects	G2D	GeneDistiller	ToppGene
1	BMP1	BMP1	CNOT7	BMP1	CSGALNACT1
2	LOXL2	LPL	CSGALNACT1	CSGALNACT1	LPL
3	SLC39A14	CSGALNACT1	HR	NPM2	BMP1
4	DOCK5	SLC39A14	ADAMDEC1	LOXL2	LOXL2
5	LPL	ADAM7	GNRH1	LPL	GNRH1
6	STC1	ADAM28	BMP1	STC1	FGF17
7	SORBS3	ADAMDEC1	NKX3-1	SLC39A14	SFTPC
8	NEFL	LOXL2	STC1	GNRH1	FGF20
9	ADAM28	FGL1	SLC39A14	HR	HR
10	ASAH1	PDLIM2	LPL	GFRA2	STC1
11	CCAR2	LZTS1	NKX2-6	NAT1	DOK2
12	FGL1	FGF17	NAT1	TNFRSF10B	DMTN
13	EGF17	KTCD9	NPM2	NKX3-1	PDLIM2
14	ENTPP4	SLC18A1	ENTPD4	SFTPC	ATP6V1B2
15	PDGFRL	PCM1	ADAM28	PDLIM2	NPM2
16	PFLIM2	DOCK5	ASAH1	TNFRSF10D	FGL1
17	LZTS1	GFRA2	FGF17	SORBS3	NEFM
18	NAT1	SLC7A1	BIN3	POLR3D	SLC39A14
19	VSP37A	C8orf20	LOXL2	ASAH1	GFRA2
20	DOK2	STC1	ATP6V1B2	DOCK5	NEFL

CSGALNACT1 is not recognized by the Endeavour web tool.