Research Article

Association between Programmed Cell Death 6 Interacting Protein Insertion/Deletion Polymorphism and the Risk of Breast Cancer in a Sample of Iranian Population

Table 1

The genotypes and allele distribution of PCD6IP 15 bp I/D (rs28381975) variants in breast cancer (BC) patients and the control group.

PCD6IP PatientsControl groupOR (95% CI) value
(%) (%)

Codominant
 D/D139 (52.3)73 (32.4)1.00
 I/D116 (43.6)137 (60.9)0.44 (0.31–0.65)<0.0001
 I/I11 (4.1)15 (6.7)0.39 (0.17–0.88)0.030
Dominant
 D/D139 (52.3)73 (32.4)1.00
 D/I + I/I127 (47.7)152 (67.6)0.44 (0.30–0.63)<0.0001
Recessive
 D/D + D/I256 (95.9)210 (93.3)1.00
 I/I11 (4.1)15 (6.7)0.60 (0.27–1.34)0.229
Allele
 D394 (74.1)283 (62.9)1.00
 I138 (25.9)167 (37.1)0.59 (0.45–0.78)<0.001