Research Article

The Role of Circulating Tight Junction Proteins in Evaluating Blood Brain Barrier Disruption following Intracranial Hemorrhage

Table 2

General characters of patients with intracranial hemorrhage and the controls.

 Intracranial hemorrhageControls

Age (yrs)55.05 (49.18–60.91)23.88 (14.70–33.06)
M/F12/1014/3
SBP (mmHg)175.5 (157.00–190.50)121.00 (100.50–133.00)
DBP (mmHg)104.50 (94.50–111.25)70.00 (66.50–82.00)
WBC (/L)11.94 (10.04–15.11)7.61 (5.93–11.04)
RBC (/L)4.14 (3.80–4.48)4.51 (4.27–4.75)
Hb (g/L)123.95 (115.29–132.63)128.06 (118.76–137.35)
PLT (/L)193.50 (143.00–246.00)239.00 (169.00–313.00)
LDH (U/L)247.14 (215.16–279.11)201.29 (166.33–236.26)
AST (U/L)47.50 (30.00–88.00)26.00 (24.00–44.00)
ALT (U/L)38.00 (19.00–90.00)21.00 (15.00–33.00)
GGT (U/L)52.50 (23.00–88.00)17.00 (12.00–24.00)
ALP (U/L)73.50 (56.00–87.00)90.00 (54.00–154.00)
CHE (U/L)5.85 (4.90–6.81)7.16 (6.41–7.91)
TP (g/L)65.71 (61.68–69.74)67.50 (64.19–70.81)
ALB (g/L)36.36 (34.09–38.63)39.35 (37.90–40.81)
Glu (mmol/L)3.93 (2.98–4.26)3.52 (3.31–4.16)
Cl (mmol/L)121.17 (118.68–123.65)125.96 (122.75–129.17)
ALB (g/L)0.93 (0.78–1.08)0.43 (0.30–0.55)
WBC (/L)52.50 (28.00–233.50)11.00 (4.50–41.50)
BBB ratio22.68 (17.46–32.79)9.69 (6.27–13.23)

M: male; F: female; SBP: systolic blood pressure; DBP: diastolic blood pressure; CSF: cerebrospinal fluid; WBC: white blood cell; RBC: red blood cell; Hb: hemoglobin; PLT: platelet; LDH: L-lactate dehydrogenase; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: gamma-glutamyl transpeptidase; ALP: alkaline phosphatase; CHE: cholinesterase; TP: total protein; Alb: albumin; GLB: globulin; Glu: glucose; Cl: chlorine; BBB ratio: Alb × 1000/Alb.
and when the intracranial hemorrhage group is compared with control.