NRAMP1 and VDR Gene Polymorphisms in Susceptibility to Tuberculosis in Venezuelan Population

Table 2

Genotype and allele frequency distribution of VDR gene in the controls and TB patients.

Fok1	ff	Ff	FF	Total
Genotypes
Controls (number of individuals)	16	60	26	102
% of total	8.2	30.8	13.3	52.3
% within condition	15.7	58.8	25.5
% within Fok1	57.1	56.1	43.3
TB patients (number of individuals)	12	47	34	93
% of total	6.2	24.1	17.4	47.7
% within condition	12.9	50.5	36.6
% within Fok1	42.9	43.9	56.7
Total	28	107	60	195
% of total	14.4	54.9	30.7	100
(df: 2) = 2.81      Cramer’s
Taq1	tt	Tt	TT	Total
Genotypes
Controls (number of individuals)	1	38	58	97
% of total	0.5	20.8	31.7	53
% within condition	1	39.2	59.8
% within Taq1	33.3	53.5	53.2
TB patients (number of individuals)	2	33	51	86
% of total	1.1	18	27.9	47
% within condition	2.3	38.4	59.3
% within Taq1	66.7	46.5	46.8
Total	3	71	109	183
% of total	1.6	38.8	59.6	100
(df: 2) = 0.48      Cramer’s
Apa1	aa	Aa	AA	Total
Genotypes
Controls (number of individuals)	18	54	29	101
% of total	9.5	28.4	15.3	53.2
% within condition	17.8	53.5	28.7
% within Apa1	47.4	56.3	51.8
TB patients (number of individuals)	20	42	27	89
% of total	10.5	22.1	14.2	46.8
% within condition	22.5	47.2	30.3
% within Apa1	66.7	46.5	46.8
Total	38	96	56	190
% of total	20	50.5	29.5	100
(df: 2) = 0.92      Cramer’s

Note. : probability values; df: degree freedom; Cramer’s : measure of association between two variables.