Disease Markers / 2015 / Article / Tab 2

Research Article

The Prognostic Value of Intermedin in Patients with Breast Cancer

Table 2

The factors associated with overall survival and disease-free survival during 5-year follow-up.

CharacteristicsOverall survivalDisease-free survival
Hazard ratio
(95% confidence interval)
Univariate analysis
values
Hazard ratio
(95% confidence interval)
Univariate analysis
values

Age
(≥45 y versus ≤44 y)
1.431 (0.851–2.409)0.1771.240 (0.812–1.894)0.319
Menopausal status
(postmenopausal versus premenopausal)
1.720 (1.037–2.853)0.0361.666 (1.097–2.532)0.017
Tumor size
(≥2 cm versus <2 cm)
2.336 (1.381–3.950)0.0021.885 (1.236–2.875)0.003
Tumor-mode-metastasis stage
(III versus I, II)
2.112 (1.270–3.514)0.0041.787 (1.166–2.741)0.008
Lymph node status
(positive versus negative)
2.817 (1.656–4.790)<0.0012.328 (1.521–3.563)<0.001
Histologic grade
(III versus I, II)
2.453 (1.451–4.148)0.0012.010 (1.318–3.067)0.001
Nuclear grade
(III versus I, II)
2.277 (1.347–3.851)0.0021.853 (1.215–2.827)0.004
Estrogen receptor status
(negative versus positive)
2.695 (1.585–4.582)<0.0012.188 (1.432–3.343)<0.001
Progesterone receptor status
(negative versus positive)
2.098 (1.247–3.532)0.0051.753 (1.151–2.671)0.009
Intermedin
(high versus low)
5.438 (3.029–9.763)<0.0014.885 (3.084–7.739)<0.001

Univariate Cox’s regression analysis was used to calculate the Hazard ratio and 95% confidence interval.