Research Article
Association of DNA Repair Gene APE1 Asp148Glu Polymorphism with Breast Cancer Risk
Table 2
Genotype distribution of APE1 gene polymorphism in breast cancer cases and controls.
| Genotype | Cases | Controls | OR | 95% CI | | value |
| rs1130409 | | | | | | | Asp/Asp | 12 (0.12) | 27 (0.27) | Ref | | | | Asp/Glu | 45 (0.45) | 46 (0.46) | 2.201 | 0.994–4.872 | 3.87 | 0.04917 | Glu/Glu | 43 (0.43) | 27 (0.27) | 3.583 | 1.558–8.243 | 9.42 | 0.00215 | Asp/Glu + Glu/Glu | 88 (0.88) | 73 (0.73) | 2.712 | 1.284–5.727 | 7.17 | 0.00743 | Asp | 69 (0.345) | 100 (0.5) | Ref | | | | Glu | 131 (0.65) | 100 (0.5) | 1.899 | 1.270–2.839 | 9.85 | 0.00170 |
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