IL-4 Gene Polymorphism May Contribute to an Increased Risk of Atopic Dermatitis in Children

Table 6

Effect of IL-4 single nucleotide polymorphisms, 590C/T and 589C/T, on the serum IL-4 level in the case group and the control group.

	Genotypes	Case group	Control group
590C/T	CC	37.27 ± 9.12	36.41 ± 7.32	0.154	0.882
	CT	74.11 ± 19.28	37.90 ± 6.26	7.545	0.000
	TT	90.82 ± 25.12	39.30 ± 4.16	15.930	0.000
589C/T	CC	89.26	34.02 ± 6.43	—	—
	CT	55.31 ± 15.82	36.52 ± 8.71	4.334	0.000
	TT	91.59 ± 24.26	40.16 ± 7.37	16.420	0.000

Note: , compared with wild homozygotes; , compared with heterozygote.