Two tagSNPs rs352493 and rs3760908 within SIRT6 Gene Are Associated with the Severity of Coronary Artery Disease in a Chinese Han Population

Table 4

Association between haplotypes of tagSNPs in SIRT6 gene with the risk of CAD.

Haplotype	Controls	Cases	OR (95% CI)
	Number (%)	Number (%)
Total
GCCTA	328.69 (25.1)	223.42 (23.6)	0.93 (0.76–1.12)	0.432
GCTCG	86.43 (6.6)	71.83 (7.6)	1.17 (0.84–1.61)	0.356
GCTTA	108.25 (8.3)	62.54 (6.6)	0.79 (0.57–1.09)	0.145
GCTTG	266.76 (20.4)	214.82 (22.7)	1.15 (0.94–1.41)	0.174
GTTCG	385.25 (29.4)	274.28 (28.9)	0.98 (0.82–1.18)	0.846
TCTTA	125.02 (9.5)	90.91 (9.6)	1.01 (0.76–1.34)	0.950

The allelic sequence in the haplotypes is in the following order: rs11878868, rs107251, rs352493, rs4807546, rs3760908.