Research Article

Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice

Table 1

Body weight, serum lipids, and hydroxyproline in three groups of mice.

Parameters MockLenti-EGFPLenti-P4Hα1
() () ()

Body Weight (g) 30.45 ± 0.3931.12 ± 0.2829.98 ± 0.76
TC (mmol/L)1.24 ± 0.191.32 ± 0.211.28 ± 0.31
TG (mmol/L)1.03 ± 0.091.12 ± 0.121.21 ± 0.14
LDL-C (mmol/L)6.36 ± 0.716.54 ± 0.586.28 ± 0.56
HDL-C (mmol/L)1.91 ± 0.351.89 ± 0.421.92 ± 0.31
Hydroxyproline (mg/mL)1.78 ± 0.351.83 ± 0.413.09 ± 0.41

TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.
< 0.05 versus mock group, < 0.05 versus lenti-EGFP group.