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Disease Markers
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2016
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Article
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Tab 2
/
Research Article
Effects of Ramipril and Telmisartan on Plasma Concentrations of Low Molecular Weight and Protein Thiols and Carotid Intima Media Thickness in Patients with Chronic Kidney Disease
Table 2
Drug effects on blood pressure and renal function markers.
Group 1 (
)
Group 2 (
)
Baseline
Telmisartan/ramipril
40/5 mg/day
value
Baseline
Telmisartan
80 mg/day
value
Mean ± SD
or median (IQR)
Mean ± SD
or median (IQR)
Mean ± SD
or median (IQR)
Mean ± SD
or median (IQR)
Systolic BP, mmHg
132 ± 13
122 ± 10
0.04
133 ± 14
123 ± 15
0.11
Diastolic BP, mmHg
82 ± 8
75 ± 5
0.02
77 ± 9
76 ± 10
0.80
Creatinine, mg/dL
1.6 (1.0–2.3)
1.5 (1.1–2.2)
0.57
1.7 (1.3–2.0)
1.5 (1.3–2.0)
0.85
GFR, mL/min per 1.73 m
2
48 (22–71)
47 (23–61)
0.79
48 (34–66)
55 (36–71)
0.79
Proteinuria, g/24 h
0.52 (0.28–2.49)
0.49 (0.22–1.15)
0.07
1.28 (0.36–2.35)
0.67 (0.44–1.68)
0.08