Discovery and Validation of Hypermethylated Markers for Colorectal Cancer

Figure 1

Distribution of DMRs in the human CRC genome. (a) Stacked bar charts showing the distribution of the hypermethylated DMRs over five gene categories: promoter, 5′UTR, 1st exon, gene body, 3′UTR, and intergenic regions. (b) Stacked bar charts showing the distribution of the hypomethylated DMRs over five gene categories: promoter, 5′UTR, 1st exon, gene body, 3′UTR, and intergenic regions. (c) Bar charts showing the distribution of the hypermethylated and hypomethylated DMRs considering four sizes: 1–400 bp, 401–800 bp, 801–1200 bp, and >1200 bp.

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