Urinary Lysosomal Enzyme Activities and Albuminuria in Ghanaian Patients with Type 2 Diabetes Mellitus

Table 2

Urinary biochemical analytes of microalbuminuric and normoalbuminuric diabetics.

Variable	Normoalbuminuria; (<30 mg/g)	Microalbuminuria; (30–300 mg/g)	value
U-creatinine (g/L)	0.76 ± 0.67	1.34 ± 0.78	0.001
U-albumin (mg/L)	22.4 ± 12.1	81.56 ± 70.3	0.001
NAG (U/L)	12.88 ± 2.07	13.28 ± 2.4	0.495
AAP (ng/mL)	4.34 ± 1.26	4.35 ± 1.32	0.989
Alb/Cr (mg/g)	17.67 ± 4.86	108.7 ± 50.1	0.001
NAG/Cr (U/g)	11.83 ± 6.76	26.7 ± 17.2	0.001
AAP/Cr (ng/g)	3.84 ± 1.91	8.6 ± 5.79	0.001
% normoalbuminuric diabetics with AAP/U-Cr and NAG/U-Cr
AAP/U-Cr		⁢9.3
NAG/U-Cr		⁢12.0

Data is presented as mean ± SD and percentages. values ≤ 0.05 were considered as statistically significant. NAG is N-acetyl--D-glucosaminidase, AAP is alanine aminopeptidase, Cr is creatinine, Alb is albumin, and U-Cr is urinary creatinine.