Research Article
Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor
Table 3
Expression of CAF-related proteins in epithelial component of phyllodes tumor according to histologic
.
| | Parameters | Total = 179 (100%) | PT, benign = 151 (100%) | PT, borderline = 23 (100%) | PT, malignant = 5 (100%) | value |
| | Podoplanin | | | | | 0.329 | | Negative | 35 (19.6) | 27 (17.9) | 6 (26.1) | 2 (40.0) | | | Positive | 144 (80.4) | 124 (82.1) | 17 (73.9) | 3 (60.0) | | | Prolyl 4-hydroxylase | | | | | 0.621 | | Negative | 174 (97.2) | 146 (96.7) | 23 (100.0) | 5 (100.0) | | | Positive | 5 (2.8) | 5 (3.3) | 0 (0.0) | 0 (0.0) | | | FAPα | | | | | 0.794 | | Negative | 166 (92.7) | 140 (92.7) | 21 (91.3) | 5 (100.0) | | | Positive | 13 (7.3) | 11 (7.3) | 2 (8.7) | 0 (0.0) | | | S100A4 | | | | | 0.571 | | Negative | 93 (52.0) | 81 (53.6) | 10 (43.5) | 2 (40.0) | | | Positive | 86 (48.0) | 70 (46.4) | 13 (56.5) | 3 (60.0) | | | PDGFRα | | | | | 0.738 | | Negative | 145 (81.0) | 121 (80.1) | 20 (87.0) | 4 (80.0) | | | Positive | 34 (19.0) | 30 (19.9) | 3 (13.0) | 1 (20.0) | | | PDGFRβ | | | | | N/A | | Negative | 179 (100.0) | 151 (100.0) | 23 (100.0) | 5 (100.0) | | | Positive | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | | | NG2 | | | | | 0.216 | | Negative | 60 (33.5) | 52 (34.4) | 5 (21.7) | 3 (60.0) | | | Positive | 119 (66.5) | 99 (65.6) | 18 (78.3) | 2 (40.0) | |
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tumors without an epithelial component were excluded.
PT, phyllodes tumor.
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