Research Article
Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor
Table 4
Expression of CAF-related proteins in the stromal component of phyllodes tumor according to histologic grade.
| | Parameters | Total = 196 (100%) | PT, benign = 153 (100%) | PT, borderline = 27 (100%) | PT, malignant = 16 (100%) | value |
| | Podoplanin | | | | | 0.728 | | Negative | 52 (26.5) | 41 (26.8) | 8 (29.6) | 3 (18.8) | | | Positive | 144 (73.5) | 112 (73.2) | 19 (70.4) | 13 (81.2) | | | Prolyl 4-hydroxylase | | | | | 0.563 | | Negative | 192 (98.0) | 149 (97.4) | 27 (100.0) | 16 (100.0) | | | Positive | 4 (2.0) | 4 (2.6) | 0 (0.0) | 0 (0.0) | | | FAPα | | | | | 0.105 | | Negative | 188 (95.9) | 149 (97.4) | 25 (92.6) | 14 (87.5) | | | Positive | 8 (4.1) | 4 (2.6) | 2 (7.4) | 2 (12.5) | | | S100A4 | | | | | 0.104 | | Negative | 65 (33.2) | 56 (36.6) | 7 (25.9) | 2 (12.5) | | | Positive | 131 (66.8) | 97 (63.4) | 20 (74.1) | 14 (87.5) | | | PDGFRα | | | | | 0.003 | | Negative | 179 (91.3) | 142 (92.8) | 26 (96.3) | 11 (68.8) | | | Positive | 17 (8.7) | 11 (7.2) | 1 (3.7) | 5 (31.2) | | | PDGFRβ | | | | | 0.034 | | Negative | 80 (40.8) | 69 (45.1) | 5 (18.5) | 6 (37.5) | | | Positive | 116 (59.2) | 84 (54.9) | 22 (81.5) | 10 (62.5) | | | NG2 | | | | | 0.695 | | Negative | 93 (47.4) | 75 (49.0) | 11 (40.7) | 7 (43.8) | | | Positive | 103 (52.6) | 78 (51.0) | 16 (59.3) | 9 (56.2) | |
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PT, phyllodes tumor.
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