Research Article
Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor
Table 5
Univariate analysis of the impact of CAF-related proteins in the stromal component of phyllodes tumor on patient prognosis using the log-rank test.
| Parameters | Number of patients Total/recurrence/metastasis | Disease-free survival | Overall survival | Median survival (95% CI) months | value | Median survival (95% CI) months | value |
| Podoplanin | | | 0.936 | | 0.494 | Negative | 52/5/3 | 160 (146–174) | | 166 (155–178) | | Positive | 144/13/5 | 166 (158–175) | | 177 (171–182) | | Prolyl 4-hydroxylase | | | n/a | | n/a | Negative | 192/18/8 | n/a | | n/a | | Positive | 4/0/0 | n/a | | n/a | | FAPα | | | 0.099 | | 0.233 | Negative | 188/16/7 | 164 (157–171) | | 172 (167–177) | | Positive | 8/2/1 | 131 (71–191) | | 162 (123–200) | | S100A4 | | | 0.607 | | 0.792 | Negative | 65/5/3 | 163 (152–174) | | 168 (159–177) | | Positive | 131/13/5 | 165 (155–174) | | 176 (170–182) | | PDGFRα | | | 0.698 | | 0.002 | Negative | 179/16/5 | 167 (159–174) | | 177 (173–182) | | Positive | 17/2/3 | 121 (102–140) | | 113 (90–136) | | PDGFRβ | | | 0.394 | | 0.087 | Negative | 80/6/1 | 164 (154–174) | | 174 (170–178) | | Positive | 116/12/7 | 163 (153–173) | | 172 (164–179) | | NG2 | | | 0.830 | | 0.216 | Negative | 93/8/2 | 145 (136–154) | | 155 (151–160) | | Positive | 103/10/6 | 165 (155–175) | | 172 (164–180) | |
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