Research Article

Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor

Table 5

Univariate analysis of the impact of CAF-related proteins in the stromal component of phyllodes tumor on patient prognosis using the log-rank test.

ParametersNumber of patients Total/recurrence/metastasisDisease-free survivalOverall survival
Median survival (95% CI) months valueMedian survival (95% CI) months value

Podoplanin0.9360.494
 Negative52/5/3160 (146–174)166 (155–178)
 Positive144/13/5166 (158–175)177 (171–182)
Prolyl 4-hydroxylasen/an/a
 Negative192/18/8n/an/a
 Positive4/0/0n/an/a
FAPα0.0990.233
 Negative188/16/7164 (157–171)172 (167–177)
 Positive8/2/1131 (71–191)162 (123–200)
S100A40.6070.792
 Negative65/5/3163 (152–174)168 (159–177)
 Positive131/13/5165 (155–174)176 (170–182)
PDGFRα0.6980.002
 Negative179/16/5167 (159–174)177 (173–182)
 Positive17/2/3121 (102–140)113 (90–136)
PDGFRβ0.3940.087
 Negative80/6/1164 (154–174)174 (170–178)
 Positive116/12/7163 (153–173)172 (164–179)
NG20.8300.216
 Negative93/8/2145 (136–154)155 (151–160)
 Positive103/10/6165 (155–175)172 (164–180)