Table of Contents Author Guidelines Submit a Manuscript
Disease Markers
Volume 2016 (2016), Article ID 4591910, 9 pages
http://dx.doi.org/10.1155/2016/4591910
Research Article

Multiplatform Biomarker Discovery for Bladder Cancer Recurrence Diagnosis

1AXO Science SAS, 34 rue du Mail, 69004 Lyon, France
2AIT Austrian Institute of Technology GmbH, Konrad-Lorenz-Straße 24, 3430 Tulln, Austria
3Department of Oncology, Faculty of Health and Medical Sciences, University of Surrey, Leggett Building, Surrey GU2 7WG, UK
4Université de Lyon, Université Lyon 1, CNRS, INSA, CPE-Lyon, ICBMS, UMR 5246, No. 43, boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France

Received 17 May 2016; Accepted 27 July 2016

Academic Editor: Roland Seiler

Copyright © 2016 Marine De Paoli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Ferlay, I. Soerjomataram, R. Dikshit et al., “Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012,” International Journal of Cancer, vol. 136, no. 5, pp. E359–E386, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Babjuk, W. Oosterlinck, R. Sylvester et al., “EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder, the 2011 update,” European Urology, vol. 59, no. 6, pp. 997–1008, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. P. E. Clark, N. Agarwal, M. C. Biagioli et al., “Bladder cancer: clinical practice guidelines in oncology,” Journal of the National Comprehensive Cancer Network, vol. 11, no. 4, pp. 446–475, 2013. View at Google Scholar · View at Scopus
  4. B. W. G. van Rhijn, M. Burger, Y. Lotan et al., “Recurrence and progression of disease in non–muscle-invasive bladder cancer: from epidemiology to treatment strategy,” European Urology, vol. 56, no. 3, pp. 430–442, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Ðug, S. Jagodić, J. Ahmetović-Ðug, Z. Selimović, and A. Sulejmanović, “Predicting recurrence of non-muscle-invasive bladder cancer after transurethral resection,” Medicinski Glasnik, vol. 13, no. 1, pp. 56–61, 2016. View at Publisher · View at Google Scholar · View at Scopus
  6. K. D. Sievert, B. Amend, U. Nagele et al., “Economic aspects of bladder cancer: what are the benefits and costs?” World Journal of Urology, vol. 27, no. 3, pp. 295–300, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. R. S. Svatek, B. K. Hollenbeck, S. Holmäng et al., “The economics of bladder cancer: costs and considerations of caring for this disease,” European Urology, vol. 66, no. 2, pp. 253–262, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. B. W. G. van Rhijn, H. G. van der Poel, and T. H. van der Kwast, “Urine markers for bladder cancer surveillance: a systematic review,” European Urology, vol. 47, no. 6, pp. 736–748, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Parker and P. E. Spiess, “Current and emerging bladder cancer urinary biomarkers,” TheScientificWorldJournal, vol. 11, pp. 1103–1112, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. O. P. J. Vrooman and J. A. Witjes, “Urinary markers in bladder cancer,” European Urology, vol. 53, no. 5, pp. 909–916, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. M. De Paoli, P. Perco, I. Mühlberger et al., “Disease map-based biomarker selection and pre-validation for bladder cancer diagnostic,” Biomarkers, vol. 20, no. 5, pp. 328–337, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. S. Lee, H. Jo, J. Her, H. Y. Lee, and C. Ban, “Ultrasensitive electrochemical detection of engrailed-2 based on homeodomain-specific DNA probe recognition for the diagnosis of prostate cancer,” Biosensors and Bioelectronics, vol. 66, pp. 32–38, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Gogalic, U. Sauer, S. Doppler, and C. Preininger, “Bladder cancer biomarker array to detect aberrant levels of proteins in urine,” The Analyst, vol. 140, no. 3, pp. 724–735, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Gogalic, U. Sauer, S. Doppler et al., “Validation of a protein panel for the non-invasive detection of recurrent non-muscle invasive bladder cancer,” Cancer Epidemiology, Biomarkers & Prevention, In press.
  15. R. J. Sylvester, A. P. M. van der Meijden, W. Oosterlinck et al., “Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials,” European Urology, vol. 49, no. 3, pp. 466–477, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. P. C. Black, “Fine-tuning Risk Stratification for Non-Muscle-invasive Bladder Cancer,” European Urology, vol. 69, no. 1, pp. 70–71, 2016. View at Publisher · View at Google Scholar · View at Scopus
  17. L. A. Kluth, P. C. Black, B. H. Bochner et al., “Prognostic and prediction tools in bladder cancer: a comprehensive review of the literature,” European Urology, vol. 68, no. 2, pp. 238–253, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. W. F. Busato Jr., G. L. Almeida, C. A. Ribas, J. M. Ribas Filho, and O. De Cobelli, “EORTC risk model to predict progression in patients with non–muscle-invasive bladder cancer: is it safe to use in clinical practice?” Clinical Genitourinary Cancer, vol. 14, no. 2, pp. 176–182, 2016. View at Publisher · View at Google Scholar
  19. S. F. Shariat, P. I. Karakiewicz, R. Ashfaq et al., “Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy,” Cancer, vol. 112, no. 2, pp. 315–325, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. C. J. Rosser, M. Chang, Y. Dai et al., “Urinary protein biomarker panel for the detection of recurrent bladder cancer,” Cancer Epidemiology Biomarkers & Prevention, vol. 23, no. 7, pp. 1340–1345, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. E. M. Gallagher, D. M. O'Shea, P. Fitzpatrick et al., “Recurrence of urothelial carcinoma of the bladder: a role for insulin-like growth factor-II loss of imprinting and cytoplasmic E-cadherin immunolocalization,” Clinical Cancer Research, vol. 14, no. 21, pp. 6829–6838, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Mahnken, I. Kausch, A. C. Feller, and S. Krüger, “E-cadherin immunoreactivity correlates with recurrence and progression of minimally invasive transitional cell carcinomas of the urinary bladder,” Oncology Reports, vol. 14, no. 4, pp. 1065–1070, 2005. View at Google Scholar · View at Scopus
  23. S. T. Reis, K. R. M. Leite, L. F. Piovesan et al., “Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of bladder cancer,” BMC Urology, vol. 12, article 18, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. M.-F. Chen, P.-Y. Lin, C.-F. Wu, W.-C. Chen, and C.-T. Wu, “IL-6 Expression regulates tumorigenicity and correlates with prognosis in bladder cancer,” PLoS ONE, vol. 8, no. 4, Article ID e61901, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. A. M. Kamat, J. Briggman, D. L. Urbauer et al., “Cytokine Panel for Response to Intravesical Therapy (CyPRIT): nomogram of changes in urinary cytokine levels predicts patient response to Bacillus Calmette-Guérin,” European Urology, vol. 69, no. 2, pp. 197–200, 2016. View at Publisher · View at Google Scholar · View at Scopus
  26. P. K. Kopparapu, S. A. Boorjian, B. D. Robinson et al., “Expression of VEGF and Its receptors VEGFR1/VEGFR2 is associated with invasiveness of bladder cancer,” Anticancer Research, vol. 33, no. 6, pp. 2381–2390, 2013. View at Google Scholar · View at Scopus
  27. J. P. Crew, T. O'Brien, M. Bradburn et al., “Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer,” Cancer Research, vol. 57, no. 23, pp. 5281–5285, 1997. View at Google Scholar · View at Scopus
  28. J. P. Crew, T. O'Brien, R. Bicknell, S. Fuggle, D. Cranston, and A. L. Harris, “Urinary vascular endothelial growth factor and its correlation with bladder cancer recurrence rates,” The Journal of Urology, vol. 161, no. 3, pp. 799–804, 1999. View at Publisher · View at Google Scholar · View at Scopus
  29. P. C.-H. Chen, H.-J. Yu, Y.-H. Chang, and C.-C. Pan, “Her2 amplification distinguishes a subset of non-muscle-invasive bladder cancers with a high risk of progression,” Journal of Clinical Pathology, vol. 66, no. 2, pp. 113–119, 2013. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Krüger, G. Weitsch, H. Büttner et al., “HER2 overexpression in muscle-invasive urothelial carcinoma of the bladder: prognostic implications,” International Journal of Cancer, vol. 102, no. 5, pp. 514–518, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Underwood, J. Bartlett, J. Reeves, D. S. Gardiner, R. Scott, and T. Cooke, “C-erbB-2 gene amplification: a molecular marker in recurrent bladder tumors?” Cancer Research, vol. 55, no. 11, pp. 2422–2430, 1995. View at Google Scholar · View at Scopus
  32. R. A. Gardiner, M. L. T. H. Samaratunga, M. D. Walsh, G. J. Seymour, and M. F. Lavin, “An immunohistological demonstration of c-erbB-2 oncoprotein expression in primary urothelial bladder cancer,” Urological Research, vol. 20, no. 2, pp. 117–120, 1992. View at Publisher · View at Google Scholar · View at Scopus
  33. R. Morgan, R. T. Bryan, S. Javed et al., “Expression of Engrailed-2 (EN2) protein in bladder cancer and its potential utility as a urinary diagnostic biomarker,” European Journal of Cancer, vol. 49, no. 9, pp. 2214–2222, 2013. View at Publisher · View at Google Scholar · View at Scopus
  34. R. C. Zangar, D. S. Daly, and A. M. White, “ELISA microarray technology as a high-throughput system for cancer biomarker validation,” Expert Review of Proteomics, vol. 3, no. 1, pp. 37–44, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. P. J. Goebell, S. L. Groshen, and B. J. Schmitz-Dräger, “Guidelines for development of diagnostic markers in bladder cancer,” World Journal of Urology, vol. 26, no. 1, pp. 5–11, 2008. View at Publisher · View at Google Scholar · View at Scopus