Novel Use for DOG1 in Discriminating Breast Invasive Carcinoma from Noninvasive Breast Lesions

Figure 3

Comparison of different MEC markers in ductal carcinoma in situ with microinvasion (×200). (a) DOG1 expression was positive in MECs and negative in myofibroblastic cells and microinvasion lesions. (b) Calponin staining in MECs with partial stromal cell staining. (c) SMMHC staining in MECs, with obvious vessel staining. (d) P63 was strictly confined to the nuclei of MECs but showed discontinuous staining patterns in ductal carcinoma in situ with microinvasion compared to the other three markers.