¹H NMR-Based Analysis of Serum Metabolites in Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats

Figure 3

OPLS-DA score plots ((a), (c), and (e)) and OPLS-DA coefficients-coded loading plots ((b), (d), and (f)). Colors on the loading plots are used to identify the altered metabolites between two groups. When the is greater than the critical value of and the VIP > 1, the peaks were marked with red color; when the is between the critical values of and , and the VIP > 1, the peaks were marked with orange color; when the is less than the critical value of or VIP < 1, the peaks were marked with blue one. (a) and (b) W1 versus W0; (c) and (d) W2-3 versus W0; and (e) and (f) W4 versus W0.

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