Research Article
Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker
Table 2
Receiver operating curve analysis of APE1/Ref-1 values in patients with bladder cancer.
| | Cut-off (ng/100 L) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
| | .2820 | 84.0 | 75.9 | 84.5 | 75.2 | | .2900 | 83.4 | 75.9 | 84.4 | 74.5 | | .2970 | 82.8 | 75.9 | 84.3 | 73.9 | | .3085 | 82.2 | 75.9 | 84.2 | 73.1 | | .3195 | 81.7 | 75.9 | 84.7 | 72.6 | | .3230 | 81.7 | 76.9 | 84.7 | 72.8 | | .3430 | 81.7 | 77.8 | 85.2 | 73.0 | | .3650 | 81.7 | 78.7 | 85.7 | 73.3 | | .3765 | 81.7 | 79.6 | 86.3 | 73.5 | | .3855 | 81.1 | 79.6 | 86.2 | 72.9 | | .3895 | 80.5 | 79.6 | 86.1 | 72.3 | | .3935 | 80.5 | 80.6 | 86.6 | 72.5 | | .3955 | 79.9 | 80.6 | 86.5 | 71.9 | | .3975 | 79.3 | 80.6 | 86.5 | 71.3 | | .4005 | 78.7 | 80.6 | 86.4 | 70.7 | | .4040 | 78.1 | 80.6 | 86.3 | 70.2 | | .4095 | 78.1 | 81.5 | 86.8 | 70.4 | | .4145 | 78.1 | 82.4 | 87.4 | 70.6 | | .4200 | 78.1 | 83.3 | 88.0 | 70.9 |
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PPV: positive predictive value; NPV: negative predictive value.
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