Research Article

The Serum Concentrations of Chemokine CXCL12 and Its Specific Receptor CXCR4 in Patients with Esophageal Cancer

Table 2

Serum levels of proteins tested in patients with esophageal cancer in comparison with healthy controls.

⁢Group testedCXCL12 
(ng/mL)
CXCR4 
(ng/mL)
CEA 
(ng/mL)
SCC-Ag 
(ng/mL)
CRP 
(ng/mL)

Control group ()Median 
(range)
0.865
(0.105–4.297)
0.932
(0.079–2.879)
1.230
(0.500–4.540)
1.000
(0.600–2.500)
1.050
(0.200–10.900)

Esophageal cancer () 
Total group
Median 
(range) 
(EC versus healthy controls)
1.277
(0.108–3.106) 
0.443
(0.049–1.516) 
2.220
(0.500–65.060) 
1.200
(0.400–8.100) 
0.567
6.500
(0.200–217.600) 

Adenocarcinoma of esophagus (AC) ()Median 
(range) 
(AC versus healthy controls)
1.118
(0.108–2.697) 
0.216
0.403
(0.049–1.516) 
1.955
(0.500–46.550) 
0.800
(0.400–2.200) 
0.154
2.800
(0.200–46.800) 

Squamous cell cancer of esophagus (ESCC) ()Median 
(range) 
(ESCC versus healthy controls) 
(AC versus ESCC)
1.501
(0.380–3.106) 

0.562
0.534
(0.076–1.466) 
0.146 
0.168
2.250
(0.500–65.060) 

0.904
1.400
(0.500–8.100) 

14.900
(0.200–217.600) 


Statistically significant when .