Disease Markers

Research Article

Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of Pathology Linked to G6PD Deficiency and Sulfomucins

Table 8

List of drug classes that were overrepresented at least fourfold in the B AND G group compared to what is predicted based on the B-only and G-only groups. The ratio was computed according to (2) in the text. B: bisphosphonates; G: GERD.


Side effect	/f₀	/f₀	/f₀	Bias

Estrogen receptor antagonists	887	50	960	58.09
Mouth and throat products	889	178	971	19.31
General anesthetic	614	442	921	9.25
Mineralocorticoids	697	488	951	8.85
Tamiflu	237	474	695	8.14
Thalidomide derivatives	806	230	900	7.25
Radiation therapy	855	271	937	6.79
Transfusion	539	268	743	6.75
Aminoglycoside antibiotics	554	408	841	6.18
Other immunosuppressants	711	286	851	5.80
Opium receptor antagonists	687	525	928	5.31
Unspecified hormones	861	359	946	5.05
Gonadotropin-releasing hormone	818	200	846	4.89
Proteasome inhibitors	792	298	882	4.62
VEGF/VEGFR inhibitors	612	359	803	4.61
Glycopeptide antibiotics	600	486	866	4.56
Aromatase inhibitors	849	307	915	4.32
Smoking cessation agents	203	329	356	4.43
Antineoplastic antibiotics	729	420	896	4.42
Recombinant human erythropoietin	753	391	889	4.09
Antiviral combinations	170	453	408	4.06