Disease Markers / 2016 / Article / Tab 1

Research Article

Is Urinary NGAL Determination Useful for Monitoring Kidney Function and Assessment of Cardiovascular Disease? A 12-Month Observation of Patients with Type 2 Diabetes

Table 1

Baseline characteristics of the studied group of 55 T2DM patients with respect to cardiovascular complications of diabetes.

Patients with cardiovascular complications ()Patients without cardiovascular complications ()

Age, years70 ± 1159 ± 150.022
Female sex10 (53)19 (53)1.0
Ischemic heart disease, (%)17 (89)
Heart failure, (%)6 (32)
Systemic atherosclerosis, (%)5 (26)
T2DM duration, years7 (4–10)5 (1–10)0.1
Hypertension, (%)16 (84)26 (72)0.3
Dyslipidemia, (%)18 (95)33 (92)0.7
BMI, kg/m232.6 ± 7.630.8 ± 5.20.5
, %6.2 (6.1–6.6)7.5 (6.2–9.4)0.2
WBC, 103/μL8.0 (5.3–9.7)7.1 (5.9–8.4)0.8
Serum creatinine, μmol/L64.5 (60.1–82.2)65.8 (58.8–76.9)0.6
eGFR, mL/min/1.73 m287 (71–94)95 (81–99)0.07
Albuminuria, mg/L12.3 (7.2–41.2)9.5 (6.3–13.4)0.048
uACR, mg/g16.0 (7.5–53.6)7.8 (3.4–13.2)0.005
uNGAL, μg/L22.3 (10.4–56.9)18.8 (8.8–42.6)0.7
uNCR, μg/g29.1 (13.4–58.8)16.2 (9.5–38.8)0.038

T2DM, type 2 diabetes mellitus; , number of patients; BMI, body mass index; , hemoglobin ; WBC, white blood cells; eGFR, estimated glomerular filtration rate; uNGAL, urine neutrophil gelatinase-associated lipocalin; uNCR, urinary NGAL/creatinine ratio; uACR, urinary albumin/creatinine ratio; NS, nonsignificant result.

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