Analysis of Urinary Prostate-Specific Antigen Glycoforms in Samples of Prostate Cancer and Benign Prostate Hyperplasia
Table 2
Identified human seminal PSA glycopeptides.
M + 3H
Glycan composition
Abundance
Peak area
Normalized
665.6575
H3N2
3.06E + 06
0.51
720.0094
H4N2
9.44E + 06
1.57
773.6926
H5N2
2.20E + 07
3.67
836.0542
H4N3F1
5.91E + 06
0.98
884.4000
H4N3S1
1.10E + 07
1.84
895.4034
H6N3
5.01E + 06
0.83
898.0755
H3N4S1
4.10E + 06
0.68
933.0860
H4N3S1F1
2.26E + 07
3.77
946.7615
H3N4S1F1
5.84E + 06
0.97
952.0931
H4N4S1
5.41E + 06
0.90
957.7649
H5N4F1
5.80E + 06
0.96
992.4352
H6N3S1
4.24E + 07
7.06
1000.7791
H4N4S1F1
1.10E + 07
1.83
1006.1107
H5N4S1
1.12E + 07
1.87
1014.4546
H3N5S1F1
7.59E + 06
1.26
1019.7863
H4N5S1
4.20E + 06
0.70
1054.7967
H5N4S1F1
1.92E + 07
3.20
1068.4722
H4N5S1F1
7.81E + 06
1.30
1103.1425
H5N4S2
2.80E + 07
4.65
1116.8181
H4N5S2
1.20E + 07
1.99
1151.8285
H5N4S2F1
6.94E + 07
11.54
1157.1601
H6N4S2
9.35E + 06
1.56
1165.5040
H4N5S2F1
2.01E + 07
3.34
(a) Monoisotopic masses are given throughout. (b) The abbreviations of glycans are shown: H: hexose (Hex); N: N-acetylhexosamine (HexNAc); S: sialic acid (NeuAc); F: fucose (dHex) (c) Normalized means the normalized abundance, which is the level of PSA glycosylation.
