Association of lincRNA-p21 Haplotype with Coronary Artery Disease in a Chinese Han Population
Table 4
Association between lincRNA-p21 gene haplotypes with the risk of CAD or MI.
Haplotype
Controls
Cases
OR (95% CI)
Number (%)
Number (%)
CAD
AAAG
132.99 (10.2)
124.70 (10.1)
1.00 (0.77–1.30)
0.994
GAAG
225.98 (17.3)
171.45 (13.9)
0.78 (0.63–0.97)
GAGA
235.99 (18.0)
242.27 (19.7)
1.12 (0.92–1.37)
0.266
GAGG
440.03 (33.6)
421.58 (34.3)
1.04 (0.88–1.22)
0.685
GGGA
274.98 (21.0)
267.15 (21.7)
1.05 (0.87–1.27)
0.633
MI
AAAG
132.99 (10.2)
60.70 (10.9)
1.09 (0.79–1.50)
0.611
GAAG
225.98 (17.3)
69.17 (12.4)
0.68 (0.51–0.91)
GAGA
235.99 (18.0)
105.28 (18.9)
1.07 (0.83–1.38)
0.624
GAGG
440.03 (33.6)
195.85 (35.1)
1.08 (0.88–1.33)
0.477
GGGA
274.98 (21.0)
123.87 (22.2)
1.08 (0.85–1.38)
0.521
The allelic sequence in the haplotypes is in the following order: rs9380586, rs4713998, rs6930083, rs6931097. Haplotype with frequency less than 3% was pooled and not analyzed. values under 0.05 were shown in bold font.
