Research Article

Identification of Factors for the Preoperative Prediction of Tumour Subtype and Prognosis in Patients with T1 Lung Adenocarcinoma

Table 2

Correlation of the resected lung adenocarcinoma classification with clinical characteristics.

VariableCategoryAIS and MIA
IAC
P value

SexMale15 (36.6)23 (50.0)0.279
Female26 (63.4)23 (50.0)

Median age (years)<

SmokingAlways smoked33 (80.5)33 (71.7)0.453
Never smoked 8 (19.5)13 (28.3)

Radiological findingPure GGO18 (43.9) 1 (2.2)<
Mixed GGO23 (56.1)28 (60.9)
Pure solid nodule 017 (36.9)

CEA [IQR (median)] (ng/mL)1.17–2.32 (1.78)1.48–4.31 (2.30)

Serum miR-183 [IQR (median)]0.232–1.63 (0.790)0.684–4.33 (1.325)

Tumour size≤10 mm36 (87.8) 6 (13.0)<
>10 to ≤20 mm 4 (9.8)26 (56.5)
>21 to ≤30 mm 1 (2.4)14 (30.5)

Lymph node metastasisAbsent41 (100.0)42 (91.3)0.119
Present 0 4 (8.7)

Visceral pleural invasionAbsent41 (100.0)37 (80.4)
Present 0 9 (19.6)

Pathological stage0/IA40 (97.6)30 (65.2)<
IB/IIA/IIB/IIIA 1 (2.4)16 (34.8)

significant p value
CEA, carcinoembryonic antigen; GGO, ground-glass opacity; IQR, interquartile range; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IAC, invasive adenocarcinoma.