The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis

Table 1

Characteristics of eligible studies included in the meta-analysis.

First author	Publication year	Country	Sample	Methods	⁢Cases		⁢Controls
					Subjects ()	Betatrophin; (Mean ± SD, pg/mL)	Subjects ()	Betatrophin; (Mean ± SD, pg/mL)
Fenzl [7]	2014	Germany	Plasma	ELISA	18	1646.5 ± 551.12	19	1643.4 ± 1002.11
Chen [8]	2014	China	Serum	ELISA	112	798.6 ± 449.78	137	692.7 ± 339.44
Espes [9]	2014	Sweden	Plasma	ELISA	27	893 ± 415.69	18	639 ± 280.01
Fu [10]	2014	USA	Serum	ELISA	14	5560 ± 2731.41	15	2190 ± 929.52
Hu [5]	2014	China	Serum	ELISA	83	613.08 ± 65.15	83	296.57 ± 52.16
Gómez-Ambrosi [6]	2014	Spain	Serum	ELISA	15	13500 ± 8800	33	45100 ± 24400
Wang [11]	2015	China	Serum	ELISA	35	1123.52 ± 319.01	31	669.15 ± 318.16
Xie [12]	2014	China	Serum	ELISA	50	412.53 ± 237.67	50	306.20 ± 283.82
Yamada [13]	2015	Japan	Serum	ELISA	30	1614 ± 647	12	300 ± 236
Guo [14]	2015	China	Serum	ELISA	56	162.56 ± 42.25	60	123.52 ± 28.19
Xie [15]	2015	China	Serum	ELISA	50	833.45 ± 456.21	50	541.68 ± 136.2