An Elevated Platelet-to-Lymphocyte Ratio Predicts Poor Prognosis and Clinicopathological Characteristics in Patients with Colorectal Cancer: A Meta-Analysis
Table 3
Metaregression analysis exploring sources of heterogeneity.
Coefficient
Standard error
Adjusted R2
Overall survival
Sampling time
0.2797
0.1995
0.18
4.16%
Metastatic status
−0.0362
0.1089
0.744
−11.16%
Sample size
−0.0006
0.0006
0.401
2.35%
Cut-off value
0.0020
0.0016
0.229
23.59%
Country
0.0277
0.1945
0.889
−11.56%
Study quality
−0.0316
0.1196
0.795
−9.52%
Disease-free survival
Sampling time
0.2377
0.4092
0.579
−14.75%
Metastatic status
−0.0380
0.2159
0.865
−19.67%
Sample size
−0.0004
0.0011
0.739
−14.88%
Cut-off value
0.0017
0.0028
0.566
−7.16%
Country
0.0376
0.3659
0.921
−19.62%
Study quality
0.0832
0.2664
0.764
−17.38%
Note: the dependent variable is the lnHR for overall survival or disease-free survival from each study; weights have been assigned according to the estimated variance of the lnHR; cancer-specific survival and recurrence-free survival were not analyzed due to a limited number of studies.
