Research Article
Overexpression of GRK3, Promoting Tumor Proliferation, Is Predictive of Poor Prognosis in Colon Cancer
Table 1
Associations of GRK3 expression with clinicopathological features in colon cancer (
).
| Variables | GRK3 expression | | Negative () | Weak () | Strong () | Value |
| Age | | | | | <65 | 25 | 20 | 32 | | ≥65 | 25 | 39 | 39 | | Gender | | | | | Male | 29 | 38 | 37 | | Female | 21 | 21 | 34 | | Location | | | | Right | 15 | 19 | 30 | | Transverse | 7 | 8 | 9 | | Left | 6 | 8 | 8 | | Sigmoid | 22 | 24 | 24 | | AJCC stage | | | | | I | 10 | 12 | 2 | | II | 26 | 20 | 27 | | III | 13 | 23 | 30 | | IV | 1 | 4 | 12 | | T stage | | | | | T1 | 3 | 3 | 0 | | T2 | 7 | 10 | 3 | | T3 | 38 | 37 | 40 | | T4 | 2 | 9 | 28 | | N stage | | | | | N0 | 37 | 33 | 31 | | N1 | 11 | 20 | 22 | | N2 | 2 | 6 | 18 | | M stage | | | | | M0 | 49 | 55 | 59 | | M1 | 1 | 4 | 12 | | Differentiation | | | | | Well | 6 | 7 | 1 | | Moderate | 34 | 42 | 41 | | Poor | 10 | 10 | 29 | |
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values are based on Chi-square and Fisher’s exact test. Significant associations between 2 categorical variables.
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