Expression of Autophagy-Related Proteins in Hürthle Cell Neoplasm Is Different from That in Follicular Neoplasm

Table 5

Univariate analysis of the influences of autophagy-related protein expression on disease-free and overall survival among patients with follicular carcinoma and Hürthle cell carcinoma (log-rank test).

Parameters	Number of patients/recurrence/death	Disease-free survival		Overall survival
		Mean survival (95% CI) (months)	value	Mean survival (95% CI) (months)	value
Beclin-1			n/a		n/a
Negative	130/11/5	n/a		n/a
Positive	9/0/0	n/a		n/a
LC3A			0.942		0.359
Negative	124/10/4	115 (109–121)		120 (115–126)
Positive	15/1/1	97 (81–112)		97 (81–112)
LC3B			n/a		n/a
Negative	114/11/5	n/a		n/a
Positive	25/0/0	n/a		n/a
p62			0.104		0.406
Negative	56/7/3	88 (79–96)		95 (89–101)
Positive	83/4/2	119 (113–125)		121 (113–128)
BNIP3			n/a		n/a
Negative	111/11/5	n/a		n/a
Positive	28/0/0	n/a		n/a

CI: confidence interval; n/a: not applicable.